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A mild increase in nutrient signaling to mTORC1 in mice leads to parenchymal damage, myeloid inflammation and shortened lifespan

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This pathway provides a muscle-based thermogenic route that operates largely independently of UCP1 (13)

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Prabhu K, Murugan K, Nareshkumar A, Ramasubramanian N, Bragadeeswaran S

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