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Therefore, our finding that SFN has an immunosuppressive effect on untransformed human T-cells may explain why treatment with SFN did not lead to amelioration of cancer severity in patients as demonstrated in a number of clinical trials ( in vitro experiments on tumor cells such as breast cancer cell and hepatocellular carcinoma cell strongly suggested that SFN has anti-tumor properties (63)

[DOI] [PubMed] [Google Scholar] 114.Wang G., Hu F.B., Mistry K.B., Zhang C., Ren F., Huo Y., Paige D., Bartell T., Hong X., Caruso D., et al

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