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Systemic inflammatory response syndrome (SIRS) following unregulated IV administration, presenting with fever above 41 degrees Celsius, acute liver injury, and clotting abnormalities, is also documented in a 2025 case report

Marjuana [ Cannabis sativa ] and hashish [ Cannabis indica ] commonly cause abnormalities of aspartate aminotransferase, alanine aminotransferase or alkaline phosphatase but serious hepatotoxicity has not been reported [42]