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For obvious reasons (limited CNS sample availability, especially in the early stages of diseases), few data on the potential molecular role of the pigment in these pathologies are available, and cause-effect studies are possible only by using experimental models

Additionally, ferritin heavy chain (FTH), a core iron-storage protein, was markedly downregulated in the ID group (Fig

as a result, those suffering from anemia are frequently unaware that they have the condition

Its role has been explored in collagen-related processes, angiogenic signaling, and cellular activity within skin-associated cell types such as fibroblasts and keratinocytes