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11,12 Notably, sporadic CRC, which represent the majority of CRC cases, exhibit extensive inflammatory infiltrates with high levels of cytokine expression in the tumor microenvironment

Burrows (1979) found that toluidine blue given intravenously to sheep at a dose of 1.1 mg/kg reduced methaemoglobin produced by sodium nitrite, although the rate of reduction could be increased by the use of higher doses

doi: 10.1126/science.abd4585 93 SudreCHMurrayBVarsavskyTGrahamMSPenfoldRSBowyerRCet al

Strikingly, the TmGst3 in yeast phase cultures showed the highest gene upregulation at 15 min after H 2 O 2 exposure, having a fivefold increase compared to the no treatment control