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Unlike many neuropeptides that exert their effects primarily through binding to specific G-protein coupled receptors with well-characterized intracellular signaling cascades, DSIP appears to influence physiological processes through several complementary mechanisms

Furthermore, changes in body composition, particularly with regard to muscle mass, may have influenced the energy expenditure findings, highlighting the need for longer-term studies to fully assess the effects of GLP-1 analogs on metabolism

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