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Identification of four immune subtypes characterized by distinct composition and functions of tumor microenvironment in intrahepatic cholangiocarcinoma

These results suggest that the genetic effects contributing to POAG may vary between populations, highlighting the importance of considering population-specific genetic architectures in complex traits

Metformin also enhances endothelial function, improves lipid metabolism, reduces the intima-media thickness of the carotid artery, and lowers the risk of cardiovascular diseases such as hypertension (Poniedziaek-Czajkowska et al., 2021)