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they should have been assessed as safe by EFSA or another competent authority, in the context of Regulation 2015/2283 (Novel Foods) or other relevant legislation

NF-kappaB is activated and promotes cell death in focal cerebral ischemia Nat Med 1999 5 : 554559 DeMeester SL, Qiu Y, Buchman TG, Hotchkiss RS, Dunnigan K, Karl IE, Cobb JP