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Description

A TAZ-ANGPTL4-NOX2 axis regulates ferroptotic cell death and chemoresistance in epithelial ovarian cancer

Next, we monitored autophagic flux in GSH-depleted cells by using a tandem fluorescent-tagged LC3 lentivirus mRFP-GFP-LC3 expression system

PMID 25766068

Therefore, despite being only a partial effector of carcinogenesis, CBS belongs to a panel of intervening players, including NF-B, KRAS, p53 and Wnt components, that contribute to metabolic rewiring and increased proliferative and invasive potential