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Preparation Condition 4 (EDTA 4 o C deproteinization): Storage at 80 o C prevents enzymatic degradation of GSH We included EDTA-treated plasma stored at 4 o C (Preparation Condition 4) as a positive control for enzymatic processes that may lead to degradation of GSH during sample storage

Influence of cigarette smoking on Vitamin C, glutathione and lipid peroxidation status

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Large-scale trials are only available for BH 4 , sepiapterin or sapropterin in phenylketonuria (Muntau et al., 2024), an autosomal recessive disorder caused by deficiency of phenylalanine hydroxylase, leading to hyperphenylalaninemia, developmental delay, behavioral problems, and reduced quality of life ( Approaches with preclinical evidence only Promoting transcriptional regulation of eNOS Several compounds have been identified to enhance eNOS transcription and promote NO production