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The development of 5-amino-1MQ also represents a broader proof-of-concept for targeting metabolic intersections as a research strategy

Its mechanism of action involves inhibiting the activity of nicotinamide-nicotinamide dinucleotide transferase (NNMT), thereby increasing levels of nicotinamide adenine dinucleotide (NAD+), a key coenzyme involved in numerous cellular reactions

For example, IV high dose vitamin C (50g/day) therapy increased plasma levels of vitamin C almost 10X compared to the levels obtained from oral supplementation (2500 mg/day)

It acts as a preservative, inhibiting bacterial growth after the vial has been opened and punctured multiple times with a syringe