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Similarly, no clinically significant ARA 290-related alterations of baseline biochemical (electrolytes, calcium, liver, kidney or pancreas) or hematological (erythrocyte, thrombocyte or leukocyte) parameters were observed

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demonstrated that baicalin inhibits airway smooth muscle cell proliferation and airway remodeling-associated gene expression, including IL13, vascular endothelial growth factor, TGF1, matrix metalloproteinases (MMP) 9, and tissue inhibitor of metalloproteinase 1 via the MAPK and RAS signaling pathways, implicating a role in preventing airway remodeling [213]