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Upon completion of the modeling process, 3 rats from the group that underwent modeling and 3 from the control group were randomly selected for preliminary evaluation to confirm the successful establishment of the KOA model

the authors hypothesized a change in the balance between thyroid hormone biosynthesis and elimination (97) an induction of microsomal enzymes as uridine diphosphate glucuronosyltransferase, and an increased T4 to T3 conversion by inducing deiodinase (98, 99)

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Research resource: small RNA-seq of human granulosa cells reveals MiRNAs in FSHR and aromatase genes