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Cognitive decline and memory problems Reduced BDNF levels correlate directly with impaired memory performance, particularly episodic and declarative memory

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New York, McGraw-Hill, 1987 Schwedes U, Althoff PH, Klempa L, Leuschner L, Mothes L, Raptis S, Wdowinski J, Usadel KH: Effect of somatostatin on bile induced acute haemorrhagic pancreatitis in the dog

This trial involving participants who had diabetes-related kidney disease is the second clinical study of senolytics to be published by Mayo, but is the first trial to show that senolytic drugs, discovered by Mayo researchers, can remove senescent cells from humans as they did in numerous studies in animals