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[PMID: 3030831] [17] van Sande J, Cochaux P, Dumont JE

Contraindications: Individuals with metal sensitivities or copper overload conditions (e.g., Wilsons disease) should avoid GHK-Cu

doi: 10.1080/01443615.2022.2144171

Sex differences in psychiatric disorders have long been recognised : the Val(158)Met polymorphism in COMT is associated with obsessive-compulsive disorder in men, with anxiety phenotypes in women, and has a greater impact on cognitive function in boys than girls with COMT activity, on average, being lower in women than men due partly to its suppression by estrogen (Harrison, Tunbridge, 2008)