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Description

NaterUMYoungbloodLSJonesJFUngerERMillerAHReevesWCet al

PMC 8065891

This is most likely attributed to the inability of the constrained 13- and 14-membered macrocycles to adopt the proper transition states required for cleavage of the N-terminal peptide bond (Andersson et al., 2011) (Figure 8)