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The two main changes to the brain are: 1

A critical role of the IL-1-IL-1R signaling pathway in skin inflammation and psoriasis pathogenesis

Shah, S

The present study aimed to evaluate the effects of trimetazidine, alone or in combination with probiotics, on inflammation, oxidative stress, and ferroptosis-related pathways in 5-FUinduced intestinal mucositis in mice, with particular focus on the Nrf2/GPx4/SLC7A11 antioxidant axis