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-Hydroxybutyrate prevents vascular senescence through hnRNP A1-mediated upregulation of Oct4

Through the thiol groups of the cysteine residues, they form tight complexes with metal ions such as Cd++ , Ag+ , Pb++ , Cu++ , Hg++ , and Zn++ as well as with the semimetal As3 (Fig

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Our data demonstrate that the adaptive metabolic response to 5FU is mediated through the inhibition of TS function, as we recapitulate these phenotypes by genetic silencing or targeted inhibition of TS using antifolates