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You Y, Qiu Y, Xu H, He R, Zhang L, Wang Z, Xia Y (2024) Effective and food-grade detoxification of multiple mycotoxins using yeast expressed manganese peroxidases

A study (Dixon et al., 2012) has found that using shRNA to knock down G6PD or 6PGD in cells or using specific inhibitors of the PPP pathway, such as 6-aminonicotinamide (6-AN), can significantly inhibit erastin-induced ferroptosis, suggesting that NADPH produced by the PPP pathway may promote ferroptosis