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Malnutrition limits building blocks for tissue synthesis

10.3390/ijms232314933 11 Gallo AfflittoG.ChouT.-H.SwaminathanS

Clustering was then run using the functions FindVariableFeatures, FindNeighbors and Findclusters with resolution = 0.8 and dims = 1:20

If the NADH/NAD+ ratio rises and GAPDH activity falls, continued aldolase activity will put more stress on the ratio by funneling substrate supply into GAPDH and encouraging it to go forward, generating more NADH, despite the scarcity of NAD+