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Behav Brain Res 316:189196 Dantzer R, OConnor J, Freund G, Johnson R, Kelley K (2008) From inflammation to sickness and depression: when the immune system subjugates the brain

Glutathione is less available for other essential tasks, like skin repair and biological defence

This updated study encourages plant breeders or farmers to develop HMs stress-tolerant plant production through a breeding program

Mounting data reveal intimate Nrf2NLRP3 crosstalk: Nrf2 activation limits the transcriptional priming of NLRP3, curtails mitochondrial ROS, and directly interferes with inflammasome assembly, whereas unchecked NLRP3 signaling feeds forward to inhibit Nrf2 and perpetuate oxidative damage (sciencedirect.com)