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Ishizuka K, Kimura T, Igata-yi R, Katsuragi S, Takamatsu J, & Miyakawa T

Enzyme-responsive drug delivery system has been demonstrated, which consist of triblock N-(2-hydroxypropyl methyl) acrylamide (HPMA) conjugated with tetrapeptide linker, which allows the high molecular weight (92 kDa) to degrade into low molecular weight (44 kDa) and deliver the paclitaxel drug at tumor site [54]

Excessive activation, as seen in sickle cell disease, leads to pathological dehydration and increased membrane stiffness

DTNB modification of SH groups of isocitrate dehydrogenase from Bacillus stearothermophilus purified by affinity chromatography