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Cruciferous Vegetable Consumption Is Associated with a Reduced Risk of Total and Cardiovascular Disease Mortality

Currently, the use of rational in vivo animal models and in vitro experimental assays is important in evaluating the effects of bioactive peptide use (99), however, it is difficult to take into account bioavailability-related factors such as gastrointestinal digestibility and peptide utilisation for the assessment of learning memory capacity using neuronal cells alone

We hypothesize that the influence of SFN on the gut microbiota is at least partly related to the effects on their habitat, i.e., the gut such as (i) alleviation of oxidative stress and inflammation in the intestine, (ii) increase of the expression of tight junction proteins, preventing excessive intestinal permeability and invasion of luminal bacteria, and (iii) promotion of gut detoxification capability via increase of activity of phase II detoxification enzymes such as GSTs

M., Rafatpanah, H., Majidi, J