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PMID: 38102573 Biomed Pharmacother Bixin prevents tubulointerstitial fibrosis in hyperuricemic nephropathy via promoting PPAR-NLRP3 interaction

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Studies have shown reduced transcription levels of genes related to iNKT cell effector functions, including Cd40l , Il18rap , Egr2 , Irf4 , Nfatc3 , Tbx21 , Ifng , Il4 , Gzma , Tnf , Tnfrsf9 and Tnfsf10 , suggesting that stress can inhibit iNKT cell function through GR signaling (102)