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doi: 10.1016/j.ejphar.2016.02.038

Its long-term safety is simply not yet established, because it remains investigational

A Brief History: From Abstinence-Only to Evidence-Based Pharmacotherapy The treatment of SUD has historically leaned heavily on abstinence and psychotherapy

A key example of a synthetic nootropic in fact the first synthesized nootropic is piracetam, the original nootropic cognitive enhancer in a long series of cholinergic racetams.(6) To demonstrate the complexity of synthetic nootropic legality: piracetam is legal to order and consume in Canada and the USA, but is barred by prescription in the U.K