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Genistein can block MCF-7 breast cancer cells by inhibition of Sonic hedgehog activity [111], and apigenin impact HH/GLI pathway in malignant mesothelioma mouse cell [112]

Takasu N, Oshiro C, Akamine H, Komiya I, Nagata A, Sato Y, et al

Sirt7 mutants including DM (S111A/H187Y) and CA (K392A/R393A/T394A/K395A/R396A/K397A/K398A) were generated by using PrimeSTAR Mutagenesis (Takara, cat