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Restoration of CPEB4 prevents muscle stem cell senescence during aging

G.TaoL.JiangJ

using cardiomyocytes exposed to hypoxia/reoxygenation, demonstrated that the silencing of Set7/9 resulted in Nrf2 stabilization and subsequent chromatin acetylation within the regulatory regions of genes coding for Heme Oxygenase 1 ( HMOX1 ) and NAD(P)H:quinone acceptor oxidoreductase ( NQO1 )