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If you are experiencing any of the symptoms associated with a deficiency, it is important to consult with a healthcare professional to determine the underlying cause and appropriate treatment plan

A synthetic derivative of HN, in which glycine in position 14 was replaced by serine (HNG), displayed 1000-fold higher efficacy and protective properties already in the nanomolar range [13]

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The samples were then quickly frozen and thawed in liquid nitrogen for 3 cycles, centrifuged at 12,000 rpm for 5 min at 4 C and the supernatant was collected