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Description

Although there are few clinical trials evaluating the safety of PPAR/ agonists in other tissues, these medications appear to be safe and well-tolerated when administered to humans, at least for brief periods

(PubMed) Kromhout D, Giltay EJ, Geleijnse JM

10.1016/j.jpedsurg.2011.03.031 279

In unstimulated cells, NF-B heterodimer (p65/p50) is sequestered in the cytosol through the interactions with a class of inhibitory proteins called IB (IB, -, and -)