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Description

Recent studies have shown that arsenic trioxide has an inhibitory effect on acute promyelocytic leukemia (APL), a hematological tumor, and on solid tumors including liver [5], lung [6] and breast cancer [7]

These mechanisms, combined with drug modification and environmental adaptation, physically protect drugs from adverse environmental effects and achieve controlled release for enhanced therapeutic outcomes

Inhibition of DLD enzymatic activity has been shown to effectively decelerate the glycolytic pathway of glucose, thereby significantly diminishing its metabolic rate (129,130)