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It is notable that salinity appears to be among the most decisive factors for the diversity and composition of the GM: Indeed, in chinook salmon (Zhao et al., 2020a), salinity was reportedly more important than water temperature with regards to the effect on GM, and in Atlantic salmon the shift from freshwater to saltwater significantly impacted the GM while diet did not show significant associations with the microbiota (Rudi et al., 2018)

Fe 3+ can act as a catalase-like nanozyme to transform H 2 O 2 into O 2 , relieving the hypoxic condition in TME and boosting oxygen-based PDT and SDT

Hippo-mediated suppression of IRS2/AKT signaling prevents hepatic steatosis and liver cancer

The dimers of NF-B are sequestered in the cytosol through noncovalent interactions with inhibitory proteins termed IBs [54, 55, 103, 104]