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420,421 Another limitation of CPPs is their limited clinical efficacy, often requiring high concentrations and doses to achieve a therapeutic effect, which can cause significant toxicity and side effects, hindering the development of clinical applications

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Ramis 1 , Andrea Cabero-Arnold 1 , Silvia Labrador 1 , Alejandro Rodrguez Vzquez 1,2 , Antonio Doncel-Moriano 1,2 , Salvatore Rudilosso, Laura Llull, Sergio Amaro, Jordi Blasco 1,2 , Luis San Roman 1,2 , Xabier Urra 1,2 , Arturo Ren 1,2 , Angel Chamorro 1,2 1 Functional Unit of Cerebrovascular Disorders, Hospital Clinic Barcelona, Barcelona, Spain, 2 Fundaci de Recerca Clnic Barcelona - Institut d'Investigacions Biomdiques August Pi i Sunyer (FRCB-IDIBAPS), Barcelona, Spain Background and Aims: Perfusion abnormalities after successful thrombectomy (eTICI2b) may contribute to poor clinical outcomes in patients with ischemic stroke

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