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In addition, p50 and p52 homodimers modulate the activation threshold of target genes either by competing with TAD-containing NF-B subunits or by constitutively binding to B sites, thereby exerting a dual repressive function [77, 78]

Vulnerability of oligodendroglia to glutamate: Pharmacology, mechanisms, and prevention

For GSDMD-mediated pyroptosis, cells were primed with 1 g/mL LPS for 6 h, then 5 g/mL LPS was transfected into cytoplasm by 0.3% (v/v) Fugene HD with Opti-MEM in 1640 medium for 16 h

The role of hPrdx6 in antioxidant defense is related to its function as an H 2 O 2 scavenger and to its unique ability to reduce membrane phospholipid hydroperoxides [34, 37]