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Margaret O

Anorectal injury following pelvic radiotherapy

In the CNS, decreased or depleted levels of BDNF are closely associated with ptau, A accumulation, neuroinflammation, and neuronal apoptosis [67]

Due to its high susceptibility to undergo hyperoxidation even at low levels of oxidative stress its chaperone function is frequently involved in the oxidative folding of various ER resident proteins, likely in cooperation with protein disulfide isomerase (PDI) [68]