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Moreover, nearly half of patients taking metformin with low or borderline vitamin B12 levels exhibited elevated homocysteine levels, suggesting a true tissue deficiency in vitamin B12 [2]

Finally, sarcosine is fully consumed during C1 metabolism

[DOI] [PubMed] [Google Scholar] 453

Addressing this concern, Hyderabad-based neurologist Dr Sudhir Kumar took to Twitter to note that while vitamin B12 deficiency is known to cause anaemia, peripheral neuropathy, dementia, psychosis and skin pigmentation, calling for supplementation, excessive vitaminB12 may have adverse effects on health and life. Excess of vitamin B12 may be hazardous 1