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(a) Gastrointestinal trials (Ulcerative Colitis) A Croatian research group conducted: A phase I safety study in healthy men A phase II trial of a rectal BPC-157 formulation for mildmoderate ulcerative colitis These are only available as abstracts and drug summaries , not as full peer-reviewed publications with methods, statistics, or adverse event profiles

The risk of reduced potency or contamination increases each day past the BUD, and the potential consequences, including injection site infections and lost therapeutic effect, outweigh the cost savings of finishing a nearly empty vial

Similarly, composite IVD replacements that combine various biomaterial strategies to mimic the native disc structure, including organized annulus fibrosus and NP components, have shown promise