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While in synthetic organic chemistry the cleavage of carbon-nitrogen bonds is notoriously difficult, we describe that N -selenoethyl cysteine (SetCys) loses its selenoethyl arm in water under mild conditions upon reduction of its selenosulfide bond

Thiol-containing drugs, such as NAC, are very protective in cell cultures by reducing dopamine-induced cell death [22]

CD73-positive extracellular vesicles promote glioblastoma immunosuppression by inhibiting T-cell clonal expansion

Thus, modulation of redox status in brain tumor cells by regulating CAT expression could serve as a potential therapeutic approach in brain cancer management