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DOI: Lightner AL, Pemberton JH and Loftus EJ, Jr

Cannabinoid combination targets NOTCH1-mutated T-cell acute lymphoblastic leukemia through the integrated stress response pathway

Regarding the genetic component, at least 240 gene loci related to inflammatory responses (mainly in the nucleotide oligomerization domain -NOD- receptors, chemokines, cytokines), autophagy, and antimicrobial peptides seem to be associated with the predisposition and occurrence of IBD [35]