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Often due to allergens and high IgE levels.[ref] More frequently involves frequent or chronic rhinitis.[ref] T2-high asthma affects about 50% or more of patients[ref] T2-Low Asthma: T2-low asthma does not have significant type 2 inflammation, and eosinophil levels are not elevated

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Mechanistically, in antioxidant activity, as a potent antioxidant, CoQ10 activates the Kelch-like ECH-associated protein 1 (KEAP1)/Nrf2/ antioxidant response element (ARE) signaling pathway, upregulating the expression and enhancing the activity of downstream antioxidant enzymes such as SOD, NQO1, and HO-1

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