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Naloxone dosing in non-cardiac arrest opioid overdose The goal with naloxone administration is to avoid worsening respiratory depression, aspiration and cardiac arrest on the one hand, while on the other hand avoiding sending the patient into severe opioid withdrawal and an agitated state

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Instead, it excretes any excess B12 through urine, which means you must regularly consume foods or supplements that contain B12 to maintain adequate levels in your body