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103 A meta-analysis included findings from six controlled trials, with a total of 501 participants, in which berberine or berberine plus metformin was compared with lifestyle intervention or metformin or other anti-diabetes medications alone

Among the derivative states in the LC pool, acetyl-LC (ALC), propionyl-LC (PLC), and isovaleryl-LC (ILC) are three types that exhibit significant biological activity and have garnered attention

Clinical trials examining ALCAR in patients with mild cognitive impairment and early-stage Alzheimer's disease show slowing of cognitive decline, with effects particularly pronounced in individuals with greater baseline cognitive impairment

coli infection following FMT prompted FDA safety alerts (215), underscoring the need for rigorous donor screening