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These subtypes can be differentiated through electrophysiological studies (EPS) and/or muscle biopsy [20]

Furthermore, the degradation of damaged mitochondria via enhanced mitophagy facilitates organelle renewal, mitigates mitochondrial aging, and preserves OXPHOS efficiency [47]

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The IHC results revealed that 29% of the cardia GCs have high levels of OLFM4 expression, yet only 14.8% of non-cardia GCs were OLFM4 high, suggesting that proximal GC is predisposed to high expression of OLFM4 (Fig