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As shown in Table 1, Mecp2 +/ NQTc mice exhibited QTc values between 380 and 410 ms (mean: 401 ms), while the corrected QT interval of Mecp2 +/ LQTc mice ranged between 460 and 550 ms (mean: 480 ms), which is significantly higher than that recorded in WT and Mecp2 +/ NQTc mice ( P 70%) in Mecp2 +/ LQTc mice than in either Mecp2 +/ NQTc or WT mice ( P 450 ms

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Cholesterol metabolism in the central nervous system during early development and in the mature animal

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