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Revolutionizing personalized medicine: synergy with multi-omics data generation, main hurdles, and future perspectives

For instance, exosome circ-PVT1 has been shown to contribute to cisplatin resistance by regulating autophagy, invasion, and apoptosis via the miR-30a-5p/YAP1 axis in gastric cancer cells (90)

Side effects are mild and usually include light bruising at the injection site or minor discomfort

Interestingly, increased nuclear translocation of Nrf2 and upregulation of HO-1 protein expression have been reported to significantly ameliorate TBI-induced behavioral deficits in TBI rats [62]