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The orbitrap parameters were a noise threshold of 5 10 3 for MS1 and 2.5 10 3 for MS2, a minimum feature height of 5 10 4 , and m/z tolerances of 10 ppm (scan-to-scan), 5 ppm (intra-sample), and 5 ppm (inter-sample)

64 Positive effects of B12, 2500 g daily sublingually for 90 days (form not reported), have also been seen in musculoskeletal pain as a side-effect of aromatase inhibitors in patients with breast cancer, with a 34% reduction of pain

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