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The uptake of extracellular glucose via GLUT1 favors increased aerobic glycolysis, and lactate, generated as a byproduct of this oxidation, which is secreted via MCT1

doi: 10.3164/jcbn.40.1 213 SassoJ

Metastasis is a cascade process, including cell invasion, degradation of basement membranes, and stromal extracellular matrix, eventually causing invasion and metastasis