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The exact cause of PTLDS is not well understood, but it may involve a combination of factors such as an ongoing immune response, tissue damage from the initial infection, and possibly the presence of co-infections

Although coffee is often claimed to increase glutathione levels and GST activity, positive effects were only found in animals and cells

Glutathione is an important water-soluble antioxidant produced by our cells and consists of three amino acids: cysteine glutamic acid glycine This antioxidant is the most abundant produced by our body, playing a major role in dealing with oxidative stress

On the other hand, because a substantial portion of ingested glutamine is utilized within the intestinal mucosa during first-pass metabolism, the fraction reaching systemic circulation is relatively limited compared with many other amino acids