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Although targeting macropinocytosis could be a key strategy for overcoming resistance to glutamine uptake blockade, further studies are necessary to examine whether macropinocytosis can overcome tumor cell resistance to glutamine antimetabolites or GLS inhibitors that target enzymes involved directly in glutamine metabolism

The fourth man developed a reversible acute encephalopathy with headache, nausea, vomiting, lethargy, recurrent motor seizures, agitation, and a diffusely slow electroencephalogram (Gross et al., 1979)

Effects of Salicylic Acid on Hormonal Cross Talk, Fatty Acids Profile, and Ions Homeostasis from Salt-Stressed Safflower