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Description

In eukaryotes, TML is the product of lysosomal or proteasomal degradation of proteins such as calmodulin, myosin, actin, cytochrome c, and histones, which contain N -methylated lysine residues from post-translational modification (Strijbis et al., 2010)

Rapid maturation and expansion of the tumor vasculature are crucial for meeting the elevated demands for nutrients and oxygen at primary and metastatic tumor sites