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Glutathione is central because it touches so many of those systems

Cell nuclei were labelled with DAPI (ThermoFisher P36941)

In contrast, Gpx1/2 knockout animals are generally healthy in the lab despite being predisposed to ileocolitis during weaning and developing commensal microbiota-dependent ileal and colonic tumors by the age of 6 months (Chu et al., 2004